The prognostic role of functional dependency in older inpatients with COVID-19

Abstract Background Coronavirus disease 2019 (COVID-19) is a pandemic infection with substantial risk of death, especially in elderly persons. Information about the prognostic significance functional status older patients COVID-19 scarce. Methods Demographic, clinical, laboratory and short-term mortality data were collected 186 consecutive aged ? 65 years hospitalized COVID-19. The compared between 4 study groups: (1) age 65–79 without severe dependency; (2) 80 (3) (4) dependency. Multivariate logistic regressions performed to evaluate variables that most significantly associated entire sample. Results Statistically significant differences observed groups proportions males ( p = 0.007); diabetes mellitus 0.025), cerebrovascular < 0.001), renal failure 0.003), dementia heart 0.005), pressure sores 0.001) malignant disorders residing nursing homes 0.001). Compared 1 n 69) 2 28), 3 32) 57) presented lower mean serum albumin levels on admission less often treated convalescent plasma tocilizumab remdesivir overall rate was 23.1 %. higher group than ? 3: 45.6 % vs. 8.7 %, 17.9% 18.3 respectively On multivariate analysis, both dependency among cohort (odds ratio [OR] 4.83, 95 confidence interval [CI] 1.88 12.40, 0.001 OR 2.51, CI 1.02 6.15, 0.044, respectively). Age (group 4) remained one (OR 10.42, 3.27–33.24 Conclusions Among COVID-19, association stronger those years. Assessment may contribute decision making for care inpatients